Pharmacy

What Is The Role Of Smooth Muscles and diaphragm in the human body?

What Is The Role Of Smooth Muscles

Smooth muscles is also known as –

  1. Non-striated muscles
  2. Involuntary muscles
  3. Visceral muscles

Location :-

These muscles are present in almost all organs, for example :-

  1. In wall of digestive tract
  2. Respiratory tract
  3. Urinary bladder, ureter, urethra
  4. Blood vessel wall
  5. Muscle of iris, eyeball

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Smooth muscle structure :-


Smooth muscle fibers are fusiform, elongated cell of different length. The nucleus is single and centrally placed, well-defined myofibrils and sarcomeres are absent in smooth muscle cells.

Absence of dark and light bands gives it non-striated appearance. The contractile protein are action, myosin and tropomyosin.

Smooth muscle fibers are surrounded by connective tissue, but you won’t find any tendons in this particular muscle type.

Type :-

  1. Single unite fibers
  2. Multi unit fibers

Single unite fibers :- The muscles are arranged in single sheet or bundles. Ex.- Muscle fibers in the wall of GIT , uterus, ureters.

Multi unite fibers :- The muscle fibers are individuals and each is supplied by a single nerve. These fibers do not exhibit spontaneous contraction. ex.- Ciliary muscle of eye, smooth muscle of blood vessels.

Diaphragm :-

Diaphragm is the muscular sheet that separates the abdominal cavity and thoracic cavity. It has mainly 2 surfaces.

  1. Superior ( inlet of thorax )
  2. Inferior ( outlet of thorax )

a.) Superior surface :-

The diaphragm is in two halves-right and left. Each half is known as suprapleural membrane.

b.) Inferior surface :-

Inferior surface is also called ‘ thoraco-abdominal surface’ .

Large opening in the diaphragm :-

  1. Aortic opening :- It lies at the lower border of 12th thoracic vertebra. It transmits – aorta, thoracic, ducts and azygous vein.
  2. Oesophageal opening :- It lies in the muscular part of the diaphragm. It transmits :-
    • Esophagus
    • Gastric nerve
    • Left gastric artery
    • Vena Caval opening :- It is lies in the central tendon of diaphragm. It transmits :-

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➥ Inferior vena cava

➥ Branches of phrenic nerves

Small opening in the diaphragm :-

There are several small openings in the diaphragm which allow passage of following structures –

  • Splanchnic nerves
  • Sympathetic chain
  • Sub- costal nerves
  • Epigastric vessels

Thymus :-

Thymus is a lymphoid organ situated in the lower part of the neck extending to the superior mediastinum of thorax.

External features :- Thymus is a bi-lobed structure. It has two pyramid shaped lobes connected by areolar tissue.

weight = 10-15 gm at birth , 30-40 gm or puberty

Relations :-
  • Anterior = Sternum
  • Posterior =Arch of aorta, trachea.
  • Laterally = Lungs.
  • Inferior = Heart

Blood supply :- The thymousis supplied by branches from internal thoracic and inferior thyroid arteries.

Vein drain thoracic :- left brachio cephalic, internal thoracic vein and inferior thyroid veins.

Function :-
  • It controls lymphopoiesis and regulates the numbers of lymphocytes.
  • It regulates the development of lymphoid tissue.

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Histology :-

Parenchyma of the thymus gland contains lymphoid tissue. Cells of lymphoid tissue forms T and B lymphocytes. Lymphoid cell of thymus gland secrets thymosin hormone.

Function of thymus gland :-

Endocrine :- Thymus gland secrets maintains normal function of different lymphoid organs.

Thymus gland forms T and B lymphocyte cell. T lymphocyte cell is related with cell mediated immunity which B lymphocyte are related with antibody mediated immunity.

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